Cell cycle distribution patterns and generation times of L929 fibroblast cells persistently infected with Coxiella burnetii
نویسندگان
چکیده
منابع مشابه
Susceptibility of Coxiella burnetii to pefloxacin and ofloxacin in ovo and in persistently infected L929 cells.
The relative lack of efficacy of the antibiotic treatment of chronic Q fever endocarditis justifies the further evaluation of the susceptibility of Coxiella burnetii to the modern quinolone antibiotics. We evaluated the efficacies of pefloxacin and ofloxacin in controlling the Nine Mile isolate of C. burnetii by using an embryonated egg assay and persistently infected L929 cells in culture. Pef...
متن کاملCorrelation of DNA, RNA, and protein content by flow cytometry in normal and Coxiella burnetii-infected L929 cells.
L929 cell populations persistently infected for more than 600 days exhibited cell cycle distributions and generation times similar to those of uninfected cells. The RNA and protein contents of these long-term-infected cells, as determined by flow cytometry and correlated with the cell cycle, were likewise approximately the same as those in normal uninfected cells. Also, the ratios of RNA to DNA...
متن کاملThe evaluation of cytotoxicity of suab1 on l929 fibroblast cell line and the comparison with formocresol
Formocresol is common treatment in exposed pulp of primary teeth at caries, trauma and damaged with cavity preparation. Although, clinical and radiographic success and good clinical results are observed, dentistry societies are still searching for materials interchangeable with formocresol. Suab1 is a phytochemical agent that was selected because of its anti- bleeding effect. In this study, we ...
متن کاملThe evaluation of cytotoxicity of suab1 on l929 fibroblast cell line and the comparison with formocresol
Formocresol is common treatment in exposed pulp of primary teeth at caries, trauma and damaged with cavity preparation. Although, clinical and radiographic success and good clinical results are observed, dentistry societies are still searching for materials interchangeable with formocresol. Suab1 is a phytochemical agent that was selected because of its anti- bleeding effect. In this study, we ...
متن کاملAntibiotic susceptibilities of two Coxiella burnetii isolates implicated in distinct clinical syndromes.
Antibiotic susceptibility testing of two isolates of the Q-fever agent, Coxiella burnetii, was performed with recently and persistently infected L929 fibroblast cells. The two genetically distinct isolates, Nine Mile and Priscilla, are implicated in two different clinical disease syndromes, acute and chronic Q fever, respectively. We compared the efficacies of rifampin, doxycycline, and five 4-...
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ژورنال
عنوان ژورنال: Infection and Immunity
سال: 1985
ISSN: 0019-9567,1098-5522
DOI: 10.1128/iai.47.2.366-369.1985